
E. coli Antigen Technology Platform
Prokaryotic Expression Virus-like Particle Vaccine Technology System with Independent Intellectual Property Rights
The E. coli antigen technology platform of Wantai BioPharm is one of its core advantages, which is a prokaryotic expression virus-like particle (VLP) vaccine technology system with independent intellectual property rights. This platform has broken through the key technical difficulties of prokaryotic expression protein particle assembly, and it features low production cost, high efficiency, easy scale-up, and high safety. Combining the advantages of virus-like particle vaccines such as good immunogenicity and high safety, it has been successfully applied to the Hepatitis E vaccine and the bivalent HPV vaccine, and has been extended to the development of all HPV types, as well as HBV virus and rotavirus vaccines. In addition, this platform also has good versatility and is suitable for the development of vaccines against various pathogens.

CHO Antigen Cell Technology Platform
Industrialization Platform of Eukaryotic Cell Expression System
Wantai BioPharm has established a CHO cell expression technology platform and a pilot-scale amplification technology platform with a scale of 200L. This indicates that Wantai BioPharm not only has the research and development capabilities in CHO cell expression technology but also is expanding its industrial scale to meet the production needs of more products in the future.

Polysaccharide and Conjugation Technology Platform
Key Technology for Improving Vaccine Immunogenicity
Wantai BioPharm has established a polysaccharide conjugate protein vaccine technology platform. This platform is mainly used for the development of polysaccharide conjugate vaccines. By conjugating polysaccharides with proteins, it can improve the immunogenicity and protective effect of vaccines. This technology is of great significance in preventing diseases caused by bacteria, such as infections caused by Streptococcus pneumoniae.

Protein Quality Research Technology Platform
Multi-dimensional Recombinant Protein Quality Analysis and Control
Wantai BioPharm has established a multi-dimensional recombinant protein quality analysis and control technology platform. This platform plays an important role in vaccine research and development. Through various analytical methods, it strictly controls the quality of recombinant proteins to ensure their purity, activity, and stability. This not only helps to improve the safety and effectiveness of vaccines but also provides a solid technical support for Wantai BioPharm's research and development in the field of recombinant protein vaccines.

mRNA Vaccine Technology Platform
Cutting-edge Technology in the Field of Vaccine Research and Development
Wantai BioPharm has established an mRNA vaccine research and development technology platform. mRNA vaccine technology is one of the cutting-edge technologies in the field of vaccine research and development in recent years, with advantages such as fast research and development speed and relatively simple production process. Wantai BioPharm's layout on this platform demonstrates its innovation ability in the field of vaccine research and development and its grasp of future technological trends.

Efficacy Evaluation Technology Platform
Evaluation of Vaccine Protective Effect and Immune Response
Wantai BioPharm has established a vaccine effectiveness evaluation platform. This platform is used to evaluate the protective effect and immune response of vaccines in animal models and clinical trials. Through strict efficacy evaluation, Wantai BioPharm can ensure that its vaccine products achieve the expected protective effect before they are launched on the market, providing a guarantee for public health.

New Adjuvant Technology Platform
Key Auxiliary Factor for Enhancing Vaccine Immunogenicity
Wantai BioPharm has established a technology platform for the screening and development of new adjuvants. Adjuvants are an important component of vaccines and can enhance the immunogenicity of vaccines. Through this platform, Wantai BioPharm screens and develops new adjuvants with the aim of improving the effectiveness and safety of vaccines.

Antigen Expression Platform
Integration of Multi-system Antigen Expression Technology
Wantai BioPharm has technology platforms for E. coli expression, yeast expression, mammalian cell expression, baculovirus-insect cell expression, and hybridoma cell suspension expression. It precisely adapts to factors such as protein properties, yield requirements, expression methods, and purification requirements for technology development, and obtains antigen bioactive materials with superior performance, reliable quality, flexible production capacity, and lower cost.

Antibody Screening Platform
Multi-source High-performance Antibody Development System
Wantai BioPharm not only has the advantageous murine antibody technology but also has the development capabilities of antibodies from large animals such as rabbit antibodies and sheep antibodies. It can be applied to the development and application of antibodies against different targets without species limitations, and the affinity and performance of the products are greatly guaranteed.

Analysis and Detection Platform
Comprehensive Quality Assurance of Bioactive Materials
Wantai BioPharm has established a mature analysis and detection platform for bioactive materials. On the one hand, through the research of purification technology, protein quality identification, and preservation technology, it analyzes and controls key parameters such as the purity, charge heterogeneity, and batch-to-batch stability of proteins during the mass production process according to pharmaceutical standards. On the other hand, through technologies such as chemiluminescence, colloidal gold, immunochromatography, and P-CR detection, it tests the terminal performance of bioactive materials as early as possible to ensure the competitiveness of product performance.
