Hepatitis E is increasingly recognised as an important emerging infection in developed countries; however, its heaviest burden rests in Asia and Africa, where disease is endemic and outbreaks are frequent. Surveillance in these areas is largely absent; commonly, the outbreaks go undetected and the real disease incidence is unknown, but we do know that pregnant women are disproportionately affected, with case-fatality ratios in the third trimester estimated as high as 10–25% with a high rate of stillbirths.
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Article Source: The Lancet Gastroenterology & Hepatology