EV-71

EV71 is a common cause for hand, foot and mouth disease and is sometimes associated with severe central nervous system diseases. EV71 can be detected using Beijing Wantai’s diagnostic products.

The human enterovirus 71 (EV71), the newest member of Enteroviridae, is a common cause for hand, foot and mouth disease (HFMD) and is sometimes associated with severe central nervous system diseases. Infections usually peak in June and July. An infection with EV71 can be both asymptomatic or may cause diarrhoea and rashes. Children under five are at higher risk to develop a serious infection than adults and older children.

EV71 is transmitted from person to person by direct contact and through contamination of hands or objects with infected faeces. Nose and throat secretions, saliva or fluid from blisters can also spread the virus.

EV71 can be isolated and detected in throat and stool specimens using PCR testing. Viral RNA has been detected in skin vesicle fluid, blood and urine. Earlier and easier diagnosis can be achieved using EV71-specific serological assays, including tests specific for IgM antibody such as Beijing Wantai’s EV71 IgM ELISA.

EV-71 Diagnostic Test Kits

ELISA Tests

EV71 IgM ELISA   -   View Information Pack

Beijing Wantai’s EV71 IgM ELISA is used to detect EV71 specific-IgM antibody. In the test kit micro well strips are pre-coated with antibodies directed to anti-human IgM antibodies. Once the patient’s sample is added any IgM antibodies are captured in the wells. At the same time purified EV71 antigen, and monoclonal anti-EV71 antibodies conjugated to the enzyme horseradish peroxidase are added. These will specifically react only with the EV71-IgM antibodies captured in the wells. After adding chromogen solutions into the wells, the colourless chromogens are hydrolyzed by the bound HRP-conjugate to a blue-coloured product (if EV71-IgM antibody are present). The resulting colour intensity is proportional to the amount of antibody in the sample.

Rapid Tests

EV71 IgM Rapid Test

Beijing Wantai’s EV71-IgM Rapid Test is a single use, rapid device intended for the qualitative detection of IgM-class antibodies to human enterovirus-71 (EV71) in serum, plasma or whole blood samples. It is intended to be used in clinical laboratories for early diagnosis and management of patients related to infection with EV71.

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